Journal of Nuclear Medicine: 65 (3)

March 1, 2024; Volume 65,Issue 3

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine March 1, 2024, 65 (3) 6A;

Discussions with Leaders

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Molecular Imaging in Breast Cancer
Géraldine Gebhart, Martine Piccart and David Mankoff

Journal of Nuclear Medicine March 1, 2024, 65 (3) 337-339; DOI: https://doi.org/10.2967/jnumed.124.267461

State of the Art

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Sequencing of Somatostatin-Receptor–Based Therapies in Neuroendocrine Tumor Patients
Jonathan R. Strosberg, Taymeyah Al-Toubah, Ghassan El-Haddad, Diane Reidy Lagunes and Lisa Bodei

Journal of Nuclear Medicine March 1, 2024, 65 (3) 340-348; DOI: https://doi.org/10.2967/jnumed.123.265706

Continuing Education

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The Current and Future Roles of Precision Oncology in Advanced Breast Cancer
Heather Jacene, Eric Dietsche and Jennifer Specht

Journal of Nuclear Medicine March 1, 2024, 65 (3) 349-356; DOI: https://doi.org/10.2967/jnumed.122.264882

Focus on Molecular Imaging

Open Access
Molecular Imaging of Acute Graft-Versus-Host Disease
Chiara Bernardi, Valentina Garibotto, Behnaz Mobashwera, Robert S. Negrin, Israt S. Alam and Federico Simonetta

Journal of Nuclear Medicine March 1, 2024, 65 (3) 357-361; DOI: https://doi.org/10.2967/jnumed.123.266552

Editorial

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Rethinking Dosimetry: The Perils of Extrapolated External-Beam Radiotherapy Constraints to Radionuclide Therapy
Jonathan Strosberg, Michael S. Hofman, Taymeyah Al-Toubah and Thomas A. Hope

Journal of Nuclear Medicine March 1, 2024, 65 (3) 362-364; DOI: https://doi.org/10.2967/jnumed.123.267167

Oncology

Clinical
- Open Access
  Imaging of Tumor Stroma Using ⁶⁸Ga-FAPI PET/CT to Improve Diagnostic Accuracy of Primary Tumors in Head and Neck Cancer of Unknown Primary: A Comparative Imaging Trial
  Bingxin Gu, Ziyi Yang, Xinyue Du, Xiaoping Xu, Xiaomin Ou, Zuguang Xia, Qing Guan, Silong Hu, Zhongyi Yang and Shaoli Song
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 365-371; DOI: https://doi.org/10.2967/jnumed.123.266556
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  Diagnostic Accuracy of ⁶⁸Ga-FAPI Versus ¹⁸F-FDG PET in Patients with Various Malignancies
  Nader Hirmas, Rainer Hamacher, Miriam Sraieb, Lukas Kessler, Kim M. Pabst, Francesco Barbato, Helena Lanzafame, Stefan Kasper, Michael Nader, Claudia Kesch, Bastian von Tresckow, Hubertus Hautzel, Clemens Aigner, Martin Glas, Martin Stuschke, Sherko Kümmel, Philipp Harter, Celine Lugnier, Waldemar Uhl, Boris Hadaschik, Viktor Grünwald, Jens T. Siveke, Ken Herrmann and Wolfgang P. Fendler
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 372-378; DOI: https://doi.org/10.2967/jnumed.123.266652
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  Diagnostic Performance of ⁶⁸Ga-PSMA-11 PET/CT Versus Multiparametric MRI for Detection of Intraprostatic Radiorecurrent Prostate Cancer
  Alexander Light, Stefan Lazic, Kate Houghton, Max Bayne, Martin J. Connor, Henry Tam, Hashim U. Ahmed, Taimur T. Shah and Tara D. Barwick
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 379-385; DOI: https://doi.org/10.2967/jnumed.123.266527
Translational
- Open Access
  First-in-Human Evaluation of Site-Specifically Labeled ⁸⁹Zr-Pertuzumab in Patients with HER2-Positive Breast Cancer
  Randy Yeh, Joseph A. O’Donoghue, Vetri Sudar Jayaprakasam, Audrey Mauguen, Ryan Min, Sue Park, Julia P. Brockway, Jacqueline F. Bromberg, W Iris Zhi, Mark E. Robson, Rachel Sanford, Shanu Modi, Brian J. Agnew, Serge K. Lyashchenko, Jason S. Lewis, Gary A. Ulaner and Brian M. Zeglis
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 386-393; DOI: https://doi.org/10.2967/jnumed.123.266392
- Open Access
  Design, Preclinical Evaluation, and Clinical Translation of ⁶⁸Ga-FAPI-LM3, a Heterobivalent Molecule for PET Imaging of Nasopharyngeal Carcinoma
  Liang Zhao, Yizhen Pang, Jianyang Fang, Jianhao Chen, Yangfan Zhou, Long Sun, Hua Wu, Zhide Guo, Qin Lin and Haojun Chen
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 394-401; DOI: https://doi.org/10.2967/jnumed.123.266183
Basic
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  Effectiveness of ²²⁵Ac-Labeled Anti-EGFR Radioimmunoconjugate in EGFR-Positive Kirsten Rat Sarcoma Viral Oncogene and BRAF Mutant Colorectal Cancer Models
  Anjong Florence Tikum, Jessica P. Ketchemen, Alireza Doroudi, Anand K. Nambisan, Hanan Babeker, Fabrice Ngoh Njotu and Humphrey Fonge
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 402-408; DOI: https://doi.org/10.2967/jnumed.123.266204

Theranostics

Clinical
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  The Impact of Posttreatment Imaging in Peptide Receptor Radionuclide Therapy
  Surekha Yadav, Courtney Lawhn-Heath, Alan Paciorek, Sheila Lindsay, Rebecca Mirro, Emily K. Bergsland and Thomas A. Hope
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 409-415; DOI: https://doi.org/10.2967/jnumed.123.266614
- Open Access
  Somatostatin Receptor Imaging with [¹⁸F]FET-βAG-TOCA PET/CT and [⁶⁸Ga]Ga-DOTA-Peptide PET/CT in Patients with Neuroendocrine Tumors: A Prospective, Phase 2 Comparative Study
  Suraiya Dubash, Tara D. Barwick, Kasia Kozlowski, Andrea G. Rockall, Sairah Khan, Sameer Khan, Siraj Yusuf, Angela Lamarca, Juan W. Valle, Richard A. Hubner, Mairéad G. McNamara, Andrea Frilling, Tricia Tan, Florian Wernig, Jeannie Todd, Karim Meeran, Bhavesh Pratap, Saleem Azeem, Michael Huiban, Nicholas Keat, Jingky P. Lozano-Kuehne, Eric O. Aboagye and Rohini Sharma
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 416-422; DOI: https://doi.org/10.2967/jnumed.123.266601
- FEATURED ARTICLE OF THE MONTH
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    Prostate-Specific Membrane Antigen–Targeted Radioguided Pelvic Lymph Node Dissection in Newly Diagnosed Prostate Cancer Patients with a Suspicion of Locoregional Lymph Node Metastases: The DETECT Trial
    Melline G.M. Schilham, Diederik M. Somford, Heidi V.N. Küsters-Vandevelde, Rick Hermsen, Jean Paul A. van Basten, Robert J. Hoekstra, Tom W.J. Scheenen, Martin Gotthardt, J.P. Michiel Sedelaar and Mark Rijpkema
    
    Journal of Nuclear Medicine March 1, 2024, 65 (3) 423-429; DOI: https://doi.org/10.2967/jnumed.123.266495
- INVITED PERSPECTIVE
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    The DETECT Trial: Are We on the Verge of Precision Surgery in Primary Prostate Cancer?
    Tobias Maurer, Christian Thomas and Boris Hadaschik
    
    Journal of Nuclear Medicine March 1, 2024, 65 (3) 430-431; DOI: https://doi.org/10.2967/jnumed.123.267187
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  First Safety and Efficacy Data with the Radiohybrid ¹⁷⁷Lu-rhPSMA-10.1 for the Treatment of Metastatic Prostate Cancer
  Alexander Dierks, Alexander Gäble, Andreas Rinscheid, Georgine Wienand, Christian H. Pfob, Malte Kircher, Johanna S. Enke, Tilman Janzen, Marianne Patt, Martin Trepel, Dorothea Weckermann, Ralph A. Bundschuh and Constantin Lapa
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 432-437; DOI: https://doi.org/10.2967/jnumed.123.266741
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  Differences and Common Ground in ¹⁷⁷Lu-PSMA Radioligand Therapy Practice Patterns: International Survey of 95 Theranostic Centers
  Andrea Farolfi, Wesley R. Armstrong, Loic Djaileb, Andrei Gafita, Masatoshi Hotta, Martin Allen-Auerbach, Lena M. Unterrainer, Wolfgang P. Fendler, Matthew Rettig, Matthias Eiber, Michael S. Hofman, Boris Hadaschik, Ken Herrmann, Johannes Czernin, Jeremie Calais and Matthias R. Benz
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 438-445; DOI: https://doi.org/10.2967/jnumed.123.266391

Neurology

Clinical
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  Dopamine Transporter SPECT with 12-Minute Scan Duration Using Multiple-Pinhole Collimators
  Ralph Buchert, Balazs Szabo, Akos Kovacs, Thomas Buddenkotte, Franziska Mathies, Amir Karimzadeh, Wencke Lehnert, Susanne Klutmann, Attila Forgacs and Ivayla Apostolova
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 446-452; DOI: https://doi.org/10.2967/jnumed.123.266276
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  One-Year Longitudinal Changes in Tau Accumulation on [¹⁸F]PI-2620 PET in the Alzheimer Spectrum
  Minyoung Oh, Seung Jun Oh, Sang Ju Lee, Jungsu S. Oh, Seung Yeon Seo, Soorack Ryu, Jee Hoon Roh, Jae-Hong Lee and Jae Seung Kim
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 453-461; DOI: https://doi.org/10.2967/jnumed.123.265893
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  First-in-Human Study of ¹⁸F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding
  Lindsey R. Drake, Yanjun Wu, Mika Naganawa, Ruth Asch, Chao Zheng, Soheila Najafzadeh, Richard Pracitto, Marcel Lindemann, Songye Li, Jim Ropchan, David Labaree, Paul R. Emery, Mark Dias, Shannan Henry, Nabeel Nabulsi, David Matuskey, Ansel T. Hillmer, Jean-Dominique Gallezot, Richard E. Carson, Zhengxin Cai and Yiyun Huang
  
  Journal of Nuclear Medicine March 1, 2024, 65 (3) 462-469; DOI: https://doi.org/10.2967/jnumed.123.266470
- BRIEF COMMUNICATION
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    Triggered Seizures for Ictal SPECT Imaging: A Case Series and Feasibility Study
    Sabry L. Barlatey, Camille G. Mignardot, Cecilia Friedrichs-Maeder, Kaspar Schindler, Roland Wiest, Andreas Nowacki, Matthias Haenggi, Werner J. Z’Graggen, Claudio Pollo, Axel Rominger, Thomas Pyka and Maxime O. Baud
    
    Journal of Nuclear Medicine March 1, 2024, 65 (3) 470-474; DOI: https://doi.org/10.2967/jnumed.123.266515

Molecular Imaging

Basic
- FEATURED BASIC SCIENCE ARTICLE
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    It’s a Trap! Aldolase-Prescribed C₄ Deoxyradiofluorination Affords Intracellular Trapping and the Tracing of Fructose Metabolism by PET
    Alexia Kirby, Dominic Graf, Mojmír Suchý, Nicholas D. Calvert, Thomas A. Charlton, Robert N. Ben, Christina L. Addison and Adam Shuhendler
    
    Journal of Nuclear Medicine March 1, 2024, 65 (3) 475-480; DOI: https://doi.org/10.2967/jnumed.123.266905
- BRIEF COMMUNICATION
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    Preclinical Evaluation of Gastrin-Releasing Peptide Receptor Antagonists Labeled with ¹⁶¹Tb and ¹⁷⁷Lu: A Comparative Study
    Nadine Holzleitner, Tatjana Cwojdzinski, Roswitha Beck, Nicole Urtz-Urban, Colin C. Hillhouse, Pascal V. Grundler, Nicholas P. van der Meulen, Zeynep Talip, Stijn Ramaekers, Michiel Van de Voorde, Bernard Ponsard, Angela Casini and Thomas Günther
    
    Journal of Nuclear Medicine March 1, 2024, 65 (3) 481-484; DOI: https://doi.org/10.2967/jnumed.123.266233

AI/Advanced Image Analysis

Open Access
Need for Objective Task-Based Evaluation of Image Segmentation Algorithms for Quantitative PET: A Study with ACRIN 6668/RTOG 0235 Multicenter Clinical Trial Data
Ziping Liu, Joyce C. Mhlanga, Huitian Xia, Barry A. Siegel and Abhinav K. Jha

Journal of Nuclear Medicine March 1, 2024, 65 (3) 485-492; DOI: https://doi.org/10.2967/jnumed.123.266018

The Illustrated Post

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CCK₂ Receptor–Targeted PET/CT in Medullary Thyroid Cancer Using [⁶⁸Ga]Ga-DOTA-CCK-66
Oliver Viering, Thomas Günther, Nadine Holzleitner, Alexander Dierks, Georgine Wienand, Christian H. Pfob, Ralph A. Bundschuh, Hans-Jürgen Wester, Johanna S. Enke, Malte Kircher and Constantin Lapa

Journal of Nuclear Medicine March 1, 2024, 65 (3) 493-494; DOI: https://doi.org/10.2967/jnumed.123.266380

Letters to the Editor

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Commentary on “Radioactive Iodine: A Living History”
Bennett S. Greenspan, Michael S. Hofman and John Buscombe

Journal of Nuclear Medicine March 1, 2024, 65 (3) 495; DOI: https://doi.org/10.2967/jnumed.123.267016
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[¹⁸F]FDG and Lymphomas: Still a Winning Golden Couple in the Era of FAPI-Based Radiotracers
Priscilla Guglielmo and Laura Evangelista

Journal of Nuclear Medicine March 1, 2024, 65 (3) 495-496; DOI: https://doi.org/10.2967/jnumed.123.266939
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Reply: [¹⁸F]FDG and Lymphomas: Still a Winning Golden Couple in the Era of FAPI-Based Radiotracers
Xuetao Chen and Xuejuan Wang

Journal of Nuclear Medicine March 1, 2024, 65 (3) 496-497; DOI: https://doi.org/10.2967/jnumed.123.266989

In Memoriam

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Aruna Bodapati Gambhir, 1962–2023
Christian Behrenbruch, Andrei Iagaru and Michelle L. James

Journal of Nuclear Medicine March 1, 2024, 65 (3) 498; DOI: https://doi.org/10.2967/jnumed.124.267375

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Table of Contents

This Month in JNM

Discussions with Leaders

State of the Art

Continuing Education

Focus on Molecular Imaging

Editorial

Oncology

Clinical

Translational

Basic

Theranostics

Clinical

FEATURED ARTICLE OF THE MONTH

INVITED PERSPECTIVE

Neurology

Clinical

BRIEF COMMUNICATION

Molecular Imaging

Basic

FEATURED BASIC SCIENCE ARTICLE

BRIEF COMMUNICATION

AI/Advanced Image Analysis

The Illustrated Post

Letters to the Editor

In Memoriam

In this issue

Issue highlights

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