Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET—An International Multicenter Retrospective Study

Lena M. Unterrainer; Thomas A. Hope; Wolfgang P. Fendler; Tristan Grogan; Honest Ndlovu; Wesley Armstrong; Francesco Barbato; Matthias R. Benz; Matthew B. Rettig; Amar U. Kishan; Mike Sathekge; Ken Herrmann; Johannes Czernin; Jeremie Calais

doi:10.2967/jnumed.124.268441

Research ArticleClinical Investigation

Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET—An International Multicenter Retrospective Study

Lena M. Unterrainer, Thomas A. Hope, Wolfgang P. Fendler, Tristan Grogan, Honest Ndlovu, Wesley Armstrong, Francesco Barbato, Matthias R. Benz, Matthew B. Rettig, Amar U. Kishan, Mike Sathekge, Ken Herrmann, Johannes Czernin and Jeremie Calais

Journal of Nuclear Medicine January 2025, 66 (1) 54-60; DOI: https://doi.org/10.2967/jnumed.124.268441

Lena M. Unterrainer

1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California;

2Department of Nuclear Medicine, LMU Munich, Munich, Germany;

3Bavarian Cancer Research Center (BZKF), partner site Munich, Munich, Germany;

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Thomas A. Hope

4Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California;

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Wolfgang P. Fendler

5Department of Nuclear Medicine, University Hospital Essen, Essen, Germany;

6German Cancer Consortium–University Hospital Essen, Essen, Germany;

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Tristan Grogan

7Department of Medicine Statistics Core, David Geffen School of Medicine, UCLA, Los Angeles, California;

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Honest Ndlovu

8Department of Nuclear Medicine, University of Pretoria, Pretoria, South Africa;

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Wesley Armstrong

1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California;

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Francesco Barbato

5Department of Nuclear Medicine, University Hospital Essen, Essen, Germany;

6German Cancer Consortium–University Hospital Essen, Essen, Germany;

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Matthias R. Benz

1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California;

9Department of Radiological Sciences, UCLA, Los Angeles, California;

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Matthew B. Rettig

10Departments of Medicine and Urology, David Geffen School of Medicine, UCLA, Los Angeles, California;

11Department of Medicine, VA Greater Los Angeles, Los Angeles, California; and

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Amar U. Kishan

11Department of Medicine, VA Greater Los Angeles, Los Angeles, California; and

12Department of Radiation Oncology, David Geffen School of Medicine, UCLA, Los Angeles, California

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Mike Sathekge

8Department of Nuclear Medicine, University of Pretoria, Pretoria, South Africa;

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Ken Herrmann

5Department of Nuclear Medicine, University Hospital Essen, Essen, Germany;

6German Cancer Consortium–University Hospital Essen, Essen, Germany;

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Johannes Czernin

1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California;

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Jeremie Calais

1Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California;

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Journal of Nuclear Medicine

Vol. 66, Issue 1

January 1, 2025

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Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET—An International Multicenter Retrospective Study

Journal of Nuclear Medicine Jan 2025, 66 (1) 54-60; DOI: 10.2967/jnumed.124.268441

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Low- and High-Volume Disease in Metastatic Hormone-Sensitive Prostate Cancer: From CHAARTED to PSMA PET—An International Multicenter Retrospective Study

Journal of Nuclear Medicine Jan 2025, 66 (1) 54-60; DOI: 10.2967/jnumed.124.268441

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Keywords

CHAARTED
mHSPC
PSMA
PET/CT
bone scan
aBSI
whole-body tumor volume

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