Immuno-PET/CT Imaging of Trop2 with [18F]AlF-RESCA-T4 Differentiates Lung Cancer from Inflammation

Wei Huang; Min Cao; Yanfei Wu; You Zhang; Shuxian An; Xinbing Pan; Xinyuan Zhou; Hongda Shao; Yihui Guan; Gang Huang; Fabrizia Gelardi; Arturo Chiti; Fang Xie; Jianjun Liu; Weijun Wei

doi:10.2967/jnumed.124.268751

Research ArticleBasic Science Investigation

Immuno-PET/CT Imaging of Trop2 with [¹⁸F]AlF-RESCA-T4 Differentiates Lung Cancer from Inflammation

Wei Huang, Min Cao, Yanfei Wu, You Zhang, Shuxian An, Xinbing Pan, Xinyuan Zhou, Hongda Shao, Yihui Guan, Gang Huang, Fabrizia Gelardi, Arturo Chiti, Fang Xie, Jianjun Liu and Weijun Wei

Journal of Nuclear Medicine December 2024, 65 (12) 1904-1910; DOI: https://doi.org/10.2967/jnumed.124.268751

Wei Huang

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Min Cao

2Department of Thoracic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China;

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Yanfei Wu

3Department of Nuclear Medicine and PET Center, Huashan Hospital, Fudan University, Shanghai, China;

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You Zhang

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Shuxian An

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Xinbing Pan

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Xinyuan Zhou

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Hongda Shao

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Yihui Guan

3Department of Nuclear Medicine and PET Center, Huashan Hospital, Fudan University, Shanghai, China;

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Gang Huang

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Fabrizia Gelardi

4Università Vita-Salute San Raffaele, Milan, Italy; and

5Nuclear Medicine Department, IRCCS San Raffaele, Milano, Italy

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Arturo Chiti

4Università Vita-Salute San Raffaele, Milan, Italy; and

5Nuclear Medicine Department, IRCCS San Raffaele, Milano, Italy

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Fang Xie

3Department of Nuclear Medicine and PET Center, Huashan Hospital, Fudan University, Shanghai, China;

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Jianjun Liu

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Weijun Wei

1Department of Nuclear Medicine, Institute of Clinical Nuclear Medicine, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China;

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Vol. 65, Issue 12

December 1, 2024

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Immuno-PET/CT Imaging of Trop2 with [¹⁸F]AlF-RESCA-T4 Differentiates Lung Cancer from Inflammation

Wei Huang, Min Cao, Yanfei Wu, You Zhang, Shuxian An, Xinbing Pan, Xinyuan Zhou, Hongda Shao, Yihui Guan, Gang Huang, Fabrizia Gelardi, Arturo Chiti, Fang Xie, Jianjun Liu, Weijun Wei

Journal of Nuclear Medicine Dec 2024, 65 (12) 1904-1910; DOI: 10.2967/jnumed.124.268751

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Immuno-PET/CT Imaging of Trop2 with [¹⁸F]AlF-RESCA-T4 Differentiates Lung Cancer from Inflammation

Wei Huang, Min Cao, Yanfei Wu, You Zhang, Shuxian An, Xinbing Pan, Xinyuan Zhou, Hongda Shao, Yihui Guan, Gang Huang, Fabrizia Gelardi, Arturo Chiti, Fang Xie, Jianjun Liu, Weijun Wei

Journal of Nuclear Medicine Dec 2024, 65 (12) 1904-1910; DOI: 10.2967/jnumed.124.268751

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Keywords

Trop2
immuno-PET
single-domain antibody
companion diagnostics

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Immuno-PET/CT Imaging of Trop2 with [¹⁸F]AlF-RESCA-T4 Differentiates Lung Cancer from Inflammation

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