Correlation Between In Vivo 18F-FDG PET and Immunohistochemical Markers of Glucose Uptake and Metabolism in Pheochromocytoma and Paraganglioma

Anouk van Berkel; Jyotsna U. Rao; Benno Kusters; Tuna Demir; Eric Visser; Arjen R. Mensenkamp; Jeroen A.W.M. van der Laak; Egbert Oosterwijk; Jacques W.M Lenders; Fred C.G.J. Sweep; Ron A. Wevers; Ad R. Hermus; Johan F. Langenhuijsen; Dirk P.M. Kunst; Karel Pacak; Martin Gotthardt; Henri J.L.M. Timmers

doi:10.2967/jnumed.114.137034

Research ArticleClinical Investigations

Correlation Between In Vivo ¹⁸F-FDG PET and Immunohistochemical Markers of Glucose Uptake and Metabolism in Pheochromocytoma and Paraganglioma

Anouk van Berkel, Jyotsna U. Rao, Benno Kusters, Tuna Demir, Eric Visser, Arjen R. Mensenkamp, Jeroen A.W.M. van der Laak, Egbert Oosterwijk, Jacques W.M Lenders, Fred C.G.J. Sweep, Ron A. Wevers, Ad R. Hermus, Johan F. Langenhuijsen, Dirk P.M. Kunst, Karel Pacak, Martin Gotthardt and Henri J.L.M. Timmers

Journal of Nuclear Medicine August 2014, 55 (8) 1253-1259; DOI: https://doi.org/10.2967/jnumed.114.137034

Anouk van Berkel

1Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Jyotsna U. Rao

1Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

2Department of Laboratory Medicine, Laboratory of Genetic, Endocrine and Metabolic Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands

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Benno Kusters

3Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands

4Department of Pathology, Maastricht University Medical Centre, Maastricht, The Netherlands

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Tuna Demir

1Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

2Department of Laboratory Medicine, Laboratory of Genetic, Endocrine and Metabolic Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands

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Eric Visser

5Department of Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Arjen R. Mensenkamp

6Department of Genetics, Radboud University Medical Centre, Nijmegen, The Netherlands

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Jeroen A.W.M. van der Laak

3Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands

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Egbert Oosterwijk

7Department of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands

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Jacques W.M Lenders

8Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

9Department of Medicine and Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Dresden, Germany

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Fred C.G.J. Sweep

2Department of Laboratory Medicine, Laboratory of Genetic, Endocrine and Metabolic Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands

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Ron A. Wevers

2Department of Laboratory Medicine, Laboratory of Genetic, Endocrine and Metabolic Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands

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Ad R. Hermus

1Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Johan F. Langenhuijsen

7Department of Urology, Radboud University Medical Centre, Nijmegen, The Netherlands

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Dirk P.M. Kunst

10Department of Otolaryngology, Radboud University Medical Centre, Nijmegen, The Netherlands; and

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Karel Pacak

11Eunice Kennedy Shriver, NICHD, National Institutes of Health, Bethesda, Maryland

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Martin Gotthardt

5Department of Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Henri J.L.M. Timmers

1Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands

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Correlation Between In Vivo ¹⁸F-FDG PET and Immunohistochemical Markers of Glucose Uptake and Metabolism in Pheochromocytoma and Paraganglioma

Journal of Nuclear Medicine Aug 2014, 55 (8) 1253-1259; DOI: 10.2967/jnumed.114.137034

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Correlation Between In Vivo ¹⁸F-FDG PET and Immunohistochemical Markers of Glucose Uptake and Metabolism in Pheochromocytoma and Paraganglioma

Journal of Nuclear Medicine Aug 2014, 55 (8) 1253-1259; DOI: 10.2967/jnumed.114.137034

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Keywords

pheochromocytoma
Paraganglioma
succinate dehydrogenase
Warburg Effect
18F-fluorodeoxyglucose positron emission tomography

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