Table of Contents

April 1, 2024; Volume 65,Issue 4

This Month in JNM

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This Month in JNM
Journal of Nuclear Medicine April 1, 2024, 65 (4) 8A;

Discussions with Leaders

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Advancing Neuroimaging
Julie C. Price and Henryk Barthel

Journal of Nuclear Medicine April 1, 2024, 65 (4) 499-501; DOI: https://doi.org/10.2967/jnumed.124.267651

State of the Art

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The Potential Contribution of Radiopharmaceutical Therapies in Managing Oligometastatic Disease
Amar U. Kishan, Shankar Siva, Michael S. Hofman, James Nagarajah, Ana P. Kiess, Phuoc Tran and Jeremie Calais

Journal of Nuclear Medicine April 1, 2024, 65 (4) 502-509; DOI: https://doi.org/10.2967/jnumed.123.266772

Is It Really Happening?

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Is ¹⁸F-FDG Metabolic Tumor Volume in Lymphoma Really Happening?
Sally F. Barrington, Anne-Ségolène Cottereau and Josée M. Zijlstra

Journal of Nuclear Medicine April 1, 2024, 65 (4) 510-511; DOI: https://doi.org/10.2967/jnumed.123.267022

Oncology

Clinical
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  ⁶⁸Ga-FAPI PET/CT as an Alternative to ¹⁸F-FDG PET/CT in the Imaging of Invasive Lobular Breast Carcinoma
  Ertan Sahin, Tulay Kus, Alper Aytekin, Evren Uzun, Umut Elboga, Latif Yilmaz, Yusuf B. Cayirli, Merve Okuyan, Vuslat Cimen and Ufuk Cimen
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 512-519; DOI: https://doi.org/10.2967/jnumed.123.266798
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  An ¹⁸F-FDG PET/CT and Mean Lung Dose Model to Predict Early Radiation Pneumonitis in Stage III Non–Small Cell Lung Cancer Patients Treated with Chemoradiation and Immunotherapy
  Maria Thor, Chen Lee, Lian Sun, Purvi Patel, Aditya Apte, Milan Grkovski, Annemarie F. Shepherd, Daphna Y. Gelblum, Abraham J. Wu, Charles B. Simone, Jamie E. Chaft, Andreas Rimner, Daniel R. Gomez, Joseph O. Deasy and Narek Shaverdian
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 520-526; DOI: https://doi.org/10.2967/jnumed.123.266965
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  ⁶⁸Ga-FAPI-04 PET/CT in Non–Small Cell Lung Cancer: Accurate Evaluation of Lymph Node Metastasis and Correlation with Fibroblast Activation Protein Expression
  Chongjiao Li, Qiongrong Chen, Yueli Tian, Jie Chen, Kui Xu, Zhiwei Xiao, Juan Zhong, Jianyuan Wu, Bing Wen and Yong He
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 527-532; DOI: https://doi.org/10.2967/jnumed.123.266806
Basic
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  Efficacy of [⁶⁷Cu]Cu-EB-TATE Theranostic Against Somatostatin Receptor Subtype-2–Positive Neuroendocrine Tumors
  Fabrice Ngoh Njotu, Jessica Pougoue Ketchemen, Anjong Florence Tikum, Hanan Babeker, Brian D. Gray, Koon Y. Pak, Maruti Uppalapati and Humphrey Fonge
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 533-539; DOI: https://doi.org/10.2967/jnumed.123.265997

Theranostics

Clinical
- EDITORIAL
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    PSMA PET AUC Updates: Inclusion of rh-PSMA-7.3
    Thomas A. Hope and Hossein Jadvar
    
    Journal of Nuclear Medicine April 1, 2024, 65 (4) 540; DOI: https://doi.org/10.2967/jnumed.123.267042
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  The Impact of Baseline PSMA PET/CT Versus CT on Outcomes of ²²³Ra Therapy in Metastatic Castration-Resistant Prostate Cancer Patients
  Dianne Bosch, Kim J.M. van der Velden, Irma M. Oving, Dirk N.J. Wyndaele, Leo E. Weijs, W. Dick van Schelven, Wim J.G. Oyen, Erik T. te Beek, Addy C.M. van de Luijtgaarden, Diederik M. Somford, James Nagarajah, Rick Hermsen, Niven Mehra, Winald R. Gerritsen, Maarten J. van der Doelen and Inge M. van Oort
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 541-547; DOI: https://doi.org/10.2967/jnumed.123.266654
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  Strong Correlation Between SUV_max on PSMA PET/CT and Numeric Drop-In γ-Probe Signal for Intraoperative Identification of Prostate Cancer Lesions
  Anne-Claire Berrens, Malou A. Sorbi, Maarten L. Donswijk, Hilda A. de Barros, Samaneh Azargoshasb, Matthias N. van Oosterom, Daphne D.D. Rietbergen, Elise M. Bekers, Henk G. van der Poel, Fijs W.B. van Leeuwen and Pim J. van Leeuwen
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 548-554; DOI: https://doi.org/10.2967/jnumed.123.267075
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  The Value of ⁶⁸Ga-PSMA PET/MRI for Classifying Patients with PI-RADS 3 Lesions on Multiparametric MRI: A Prospective Single-Center Study
  Jingyan Shi, Danyan Li, Mengxia Chen, Yao Fu, Shan Peng, Qing Zhang, Jing Liang, Qun Lu, Jiaming Lu, Shuyue Ai, Feng Wang, Xuefeng Qiu and Hongqian Guo
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 555-559; DOI: https://doi.org/10.2967/jnumed.123.266742
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  Prognostic Performance of RECIP 1.0 Based on [¹⁸F]PSMA-1007 PET in Prostate Cancer Patients Treated with [¹⁷⁷Lu]Lu-PSMA I&T
  Philipp E. Hartrampf, Thomas Hüttmann, Anna Katharina Seitz, Hubert Kübler, Sebastian E. Serfling, Takahiro Higuchi, Wiebke Schlötelburg, Kerstin Michalski, Andrei Gafita, Steven P. Rowe, Martin G. Pomper, Andreas K. Buck and Rudolf A. Werner
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 560-565; DOI: https://doi.org/10.2967/jnumed.123.266702
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  Single-Time-Point Renal Dosimetry Using Nonlinear Mixed-Effects Modeling and Population-Based Model Selection in [¹⁷⁷Lu]Lu-PSMA-617 Therapy
  Deni Hardiansyah, Elham Yousefzadeh-Nowshahr, Felix Kind, Ambros J. Beer, Juri Ruf, Gerhard Glatting and Michael Mix
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 566-572; DOI: https://doi.org/10.2967/jnumed.123.266268
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  Radiolabeled Somatostatin Receptor Antagonist Versus Agonist for Peptide Receptor Radionuclide Therapy in Patients with Therapy-Resistant Meningioma: PROMENADE Phase 0 Study
  Christopher Eigler, Lisa McDougall, Andreas Bauman, Peter Bernhardt, Michael Hentschel, Kristine A. Blackham, Guillaume Nicolas, Melpomeni Fani, Damian Wild and Dominik Cordier
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 573-579; DOI: https://doi.org/10.2967/jnumed.123.266817
Basic
- FEATURED BASIC SCIENCE ARTICLE
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    Interrogating the Theranostic Capacity of a MUC16-Targeted Antibody for Ovarian Cancer
    Kyeara N. Mack, Zachary V. Samuels, Lukas M. Carter, Tara D. Viray, Komal Mandleywala, Cory L. Brooks, Michael A. Hollingsworth, Prakash Radhakrishnan and Jason S. Lewis
    
    Journal of Nuclear Medicine April 1, 2024, 65 (4) 580-585; DOI: https://doi.org/10.2967/jnumed.123.266524
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  Peptide Binder to Glypican-3 as a Theranostic Agent for Hepatocellular Carcinoma
  Fanching Lin, Renee Clift, Takeru Ehara, Hayato Yanagida, Steven Horton, Alain Noncovich, Matt Guest, Daniel Kim, Katrina Salvador, Samantha Richardson, Terra Miller, Guangzhou Han, Abhijit Bhat, Kenneth Song and Gary Li
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 586-592; DOI: https://doi.org/10.2967/jnumed.123.266766
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  Development and Preclinical Evaluation of [²¹¹At]PSAt-3-Ga: An Inhibitor for Targeted α-Therapy of Prostate Cancer
  Mohamed El Fakiri, Nawal Ayada, Marius Müller, Lars Hvass, Teodor H. Gamzov, Anne Skovsbo Clausen, Nicolas M. Geis, Nils Steinacker, Ellinor Hansson, Sture Lindegren, Emma Aneheim, Holger Jensen, Ann-Christin Eder, Andreas I. Jensen, Christian B.M. Poulie, Andreas Kjaer, Matthias Eder and Matthias M. Herth
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 593-599; DOI: https://doi.org/10.2967/jnumed.123.267043

Neurology

Clinical
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  Can Internal Carotid Arteries Be Used for Noninvasive Quantification of Brain PET Studies?
  Laura Providência, Chris W.J. van der Weijden, Philipp Mohr, Joyce van Sluis, Johannes H. van Snick, Riemer H.J.A. Slart, Rudi A.J.O. Dierckx, Adriaan A. Lammertsma and Charalampos Tsoumpas
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 600-606; DOI: https://doi.org/10.2967/jnumed.123.266675

Cardiovascular

Clinical
- SPECIAL CONTRIBUTION
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    Total-Body PET/CT Applications in Cardiovascular Diseases: A Perspective Document of the SNMMI Cardiovascular Council
    Riemer H.J.A. Slart, Frank M. Bengel, Cigdem Akincioglu, Jamieson M. Bourque, Wengen Chen, Marc R. Dweck, Marcus Hacker, Saurabh Malhotra, Edward J. Miller, Matthieu Pelletier-Galarneau, René R.S. Packard, Thomas H. Schindler, Richard L. Weinberg, Antti Saraste and Piotr J. Slomka
    
    Journal of Nuclear Medicine April 1, 2024, 65 (4) 607-616; DOI: https://doi.org/10.2967/jnumed.123.266858

Pulmonary

Clinical
- Open Access
  [¹⁸F]FDG PET/CT Signal Correlates with Neoangiogenesis Markers in Patients with Fibrotic Interstitial Lung Disease Who Underwent Lung Biopsy: Implication for the Use of PET/CT in Diffuse Lung Diseases
  Joanna C. Porter, Balaji Ganeshan, Thida Win, Francesco Fraioli, Saif Khan, Manuel Rodriguez-Justo, Raymond Endozo, Robert I. Shortman, Luke R. Hoy, Toby M. Maher and Ashley M. Groves
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 617-622; DOI: https://doi.org/10.2967/jnumed.123.266445

AI/Advanced Image Analysis

Clinical
- Open Access
  Clinical Evaluation of Deep Learning for Tumor Delineation on ¹⁸F-FDG PET/CT of Head and Neck Cancer
  David G. Kovacs, Claes N. Ladefoged, Kim F. Andersen, Jane M. Brittain, Charlotte B. Christensen, Danijela Dejanovic, Naja L. Hansen, Annika Loft, Jørgen H. Petersen, Michala Reichkendler, Flemming L. Andersen and Barbara M. Fischer
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 623-629; DOI: https://doi.org/10.2967/jnumed.123.266574
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  PET/CT-Based Radiogenomics Supports KEAP1/NFE2L2 Pathway Targeting for Non–Small Cell Lung Cancer Treated with Curative Radiotherapy
  Vincent Bourbonne, Moncef Morjani, Olivier Pradier, Mathieu Hatt, Vincent Jaouen, Solène Querellou, Dimitris Visvikis, François Lucia and Ulrike Schick
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 630-634; DOI: https://doi.org/10.2967/jnumed.123.266749
- Open Access
  Promising Candidate Prognostic Biomarkers in [¹⁸F]FDG PET Images: Evaluation in Independent Cohorts of Non–Small Cell Lung Cancer Patients
  Narinée Hovhannisyan-Baghdasarian, Marie Luporsi, Nicolas Captier, Christophe Nioche, Vesna Cuplov, Erwin Woff, Nadia Hegarat, Alain Livartowski, Nicolas Girard, Irène Buvat and Fanny Orlhac
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 635-642; DOI: https://doi.org/10.2967/jnumed.123.266331
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  Deep Semisupervised Transfer Learning for Fully Automated Whole-Body Tumor Quantification and Prognosis of Cancer on PET/CT
  Kevin H. Leung, Steven P. Rowe, Moe S. Sadaghiani, Jeffrey P. Leal, Esther Mena, Peter L. Choyke, Yong Du and Martin G. Pomper
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 643-650; DOI: https://doi.org/10.2967/jnumed.123.267048

Physics and Instrumentation

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Performance Evaluation of the uMI Panorama PET/CT System in Accordance with the National Electrical Manufacturers Association NU 2-2018 Standard
Guiyu Li, Wenhui Ma, Xiang Li, Weidong Yang, Zhiyong Quan, Taoqi Ma, Junling Wang, Yunya Wang, Fei Kang and Jing Wang

Journal of Nuclear Medicine April 1, 2024, 65 (4) 652-658; DOI: https://doi.org/10.2967/jnumed.123.265929

Special Contribution

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The Accomplishments and Legacy of Saul Hertz, MD
Bennett S. Greenspan, Michael S. Hofman and John Buscombe

Journal of Nuclear Medicine April 1, 2024, 65 (4) 659-663; DOI: https://doi.org/10.2967/jnumed.124.267524

The Illustrated Post

FEATURED ARTICLE OF THE MONTH
- Open Access
  First-in-Human ²¹²Pb-PSMA–Targeted α-Therapy SPECT/CT Imaging in a Patient with Metastatic Castration-Resistant Prostate Cancer
  Matthew R. Griffiths, David A. Pattison, Melissa Latter, Kevin Kuan, Stephen Taylor, William Tieu, Thomas Kryza, Danielle Meyrick, Boon Quan Lee, Aaron Hansen, Stephen E. Rose and Simon G. Puttick
  
  Journal of Nuclear Medicine April 1, 2024, 65 (4) 664; DOI: https://doi.org/10.2967/jnumed.123.267189
Open Access
Imaging PARP Upregulation with [¹²³I]I-PARPi SPECT/CT in Small Cell Neuroendocrine Carcinoma
Honest Ndlovu, Ismaheel Lawal, Kgomotso Mokoala, Dineo Disenyane, Nonhlahla Nkambule, Sheynaz Bassa, Yonwaba Mzizi, Meshack Bida and Mike Sathekge

Journal of Nuclear Medicine April 1, 2024, 65 (4) 665-666; DOI: https://doi.org/10.2967/jnumed.123.266348

Departments

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Erratum
Journal of Nuclear Medicine April 1, 2024, 65 (4) 650-651;