TABLE 2.

Dosimetry for ⁶⁸Ga-FAPI Based on 4 Studies (N=18), for ¹⁸F-FAPI-74 Based on a Single Study (N=10), and for ⁶⁸Ga-FAP-2286 Based on a Single Study (N=6)

Organ dosimetry (mGy/MBq)	[⁶⁸Ga]Ga-FAPI-46 (n=6)	[⁶⁸Ga]Ga-FAPI-RGD (n=6)	[⁶⁸Ga]Ga-FAPI-04 (n=6)	[¹⁸F]F-FAPI-74 (n=10)	[68Ga]Ga-FAP-2286 (n=6)
Reference	Meijer 2020	Zang 2022	Wang 2021	Giesel 2021	Kline 2024
Gallbladder wall	0.0056 ± 0.0009	0.0084 ± 0.0002	< 0.0001	0.0117 ± 0.0010	0.0098 ± 0.0027
Lower large intestine wall	0.0057 ± 0.0007	0.0078 ± 0.0005	0.0003 ± 0.0001	0.0123 ± 0.0016	0.0077 ± 0.0024
Small intestine	0.0055 ± 0.0006	0.0082 ± 0.0005	< 0.0001	0.0116 ± 0.0012	0.0078 ± 0.0025
Stomach wall	0.0053 ± 0.0007	0.0120 ± 0.0027	0.0008 ± 0.0002	0.0106 ± 0.0010	0.0077 ± 0.0023
Upper large intestine wall	0.0055 ± 0.0007	0.0075 ± 0.0004	0.0003 ± 0.0001	0.0113 ± 0.0011	0.0078 ± 0.0024
Heart wall	0.0111 ± 0.0013	0.0204 ± 0.0028	< 0.0001	0.0229 ± 0.0028	0.0134 ± 0.0049
Kidneys	0.0160 ± 0.0046	0.0324 ± 0.0072	0.0002 ± 0.0001	0.0294 ± 0.0079	0.0431 ± 0.0234
Liver	0.0101 ± 0.008	0.0145 ± 0.0036	0.0003 ± 0.0001	0.0150 ± 0.0036	0.0223 ± 0.0181
Lungs	0.0050 ± 0.0007	0.0233 ± 0.0044	0.0019 ± 0.0005	0.0096 ± 0.0007	0.0142 ± 0.0053
Muscle	0.0050 ± 0.0007			0.0094 ± 0.0010
Ovaries	0.0058 ± 0.0007		0.0004 ± 0.0001	0.0125 ± 0.0016	0.0084 ± 0.0027
Pancreas	0.0057 ± 0.0008	0.0306 ± 0.0111	< 0.0001	0.0118 ± 0.0010	0.0084 ± 0.0027
Red marrow	0.0071 ± 0.001	0.0145 ± 0.0013	0.0008 ± 0.0001	0.0112 ± 0.0011	0.0060 ± 0.0019
Osteogenic cells	0.0094 ± 0.0013	0.0107 ± 0.0009		0.0153 ± 0.0014	0.0042 ± 0.0013
Spleen	0.0070 ± 0.0028	0.0225 ± 0.0095	< 0.0001	0.0167 ± 0.0044	0.0079 ± 0.0025
Testes	0.0049 ± 0.0007	0.0071 ± 0.0005	< 0.0002	0.0099 ± 0.0013	0.0073 ± 0.0025
Thymus	0.0051 ± 0.0006	0.0074 ± 0.0003	< 0.0001	0.0102 ± 0.0009	0.0075 ± 0.0023
Thyroid	0.0048 ± 0.0006	0.0331 ± 0.0074	0.0002 ± 0.0001	0.0091 ± 0.0009	0.0067 ± 0.0021
Urinary bladder wall	0.0483 ± 0.0086	0.2260 ± 0.0331	0.0058 ± 0.0071	0.0758 ± 0.0284	0.0998 ± 0.0687
Uterus	0.0095 ± 0.0054		0.0002 ± 0.0001	0.0149 ± 0.0025	0.0106 ± 0.0036
Total body	0.0058 ± 0.0012	0.0089 ± 0.0004	0.0127 ± 0.0074	0.0097 ± 0.0009	0.0082 ± 0.0025
Effective dose (mSv/MBq)	0.0078 ± 0.0013	0.0194 ± 0.0017	0.0127 ± 0.0067	0.0141 ± 0.0022	0.0116 ± 0.0047