RT Journal Article SR Electronic T1 Nuclear Medicine and Artificial Intelligence: Best Practices for Evaluation (the RELAINCE Guidelines) JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1288 OP 1299 DO 10.2967/jnumed.121.263239 VO 63 IS 9 A1 Jha, Abhinav K. A1 Bradshaw, Tyler J. A1 Buvat, Irène A1 Hatt, Mathieu A1 KC, Prabhat A1 Liu, Chi A1 Obuchowski, Nancy F. A1 Saboury, Babak A1 Slomka, Piotr J. A1 Sunderland, John J. A1 Wahl, Richard L. A1 Yu, Zitong A1 Zuehlsdorff, Sven A1 Rahmim, Arman A1 Boellaard, Ronald YR 2022 UL http://jnm.snmjournals.org/content/63/9/1288.abstract AB An important need exists for strategies to perform rigorous objective clinical-task-based evaluation of artificial intelligence (AI) algorithms for nuclear medicine. To address this need, we propose a 4-class framework to evaluate AI algorithms for promise, technical task-specific efficacy, clinical decision making, and postdeployment efficacy. We provide best practices to evaluate AI algorithms for each of these classes. Each class of evaluation yields a claim that provides a descriptive performance of the AI algorithm. Key best practices are tabulated as the RELAINCE (Recommendations for EvaLuation of AI for NuClear medicinE) guidelines. The report was prepared by the Society of Nuclear Medicine and Molecular Imaging AI Task Force Evaluation team, which consisted of nuclear-medicine physicians, physicists, computational imaging scientists, and representatives from industry and regulatory agencies.